Typically, the method is used as a rapid and sensitive screening of analgesic and anti-inflammatory drug.
The force is applied to the animal paw, which is placed on a small plinth under a cone-shaped pusher with a rounded tip, which does not hurt the animal. The 37215 is convently used with mice; however, when lower pressure is required, we offer model 37216, with applied pressure reduced to 50% and including a special chisel-shaped pusher.
The operator depresses a pedal-switch to start the mechanism which exerts the force; when the rat struggles, the operator releases the pedal and reads off the scale the force at which the animal felt pain. Additional weights are provided, to increase the force range. The Analgesy-Meter features a low voltage synchronous motor.